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  • TRUSTED SKINCARE PRODUCTS AVAILABLE IN SOUTH AFRICA

  • Buy Tretinoin Cream & Gel
    South Africa | Authentic &
    Fast Delivery     Buy Tretinoin Cream & Gel South Africa | Authentic & Fast Delivery

  • Clear, radiant skin starts here. Explore our Tretinoin Cream
    and Tretinoin Gel pharmacy-verified and dermatologist
    approved across South Africa.
    Target acne, soften fine lines, hyperpigmentation, dark spots
    and restore youthful glow with clinically proven
    tretinoin formulations.     Authentic tretinoin, dermatologist-approved and delivered discreetly in South Africa. Clear acne and revive your skin’s glow.
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Tretinoin Creams

Tretinoin Gel

Skin Brightening and Hyperpigmentation Products in South Africa

Anti-Acne & Anti-Wrinkle Treatments

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New Launches

Skinshine cream containing hydroquinone 2 percent tretinoin 0.025 percent and mometasone furoate 0.1 percent 15g pack Skinshine cream tube showing hydroquinone 2 percent tretinoin 0.025% & mometasone furoate 0.1% 15g
Quickshop Hydroquinone 2% w/w + Tretinoin 0.025% w/w + Mometasone Furoate 0.1% w/w...
Add to Cart
Cadila Pharmaceuticals Ltd Hydroquinone, Tretinoin and Mometasone Furoate Cream for Dark Patches
R 389.99 R 424.99
Add to Cart
Sunroof Sunscreen Lotion SPF 50 60ml tube with original packaging and icons with white background Sunroof Sunscreen Lotion SPF 50 by healing pharma tube front view
Quickshop Medical-Grade Sunroof Sunscreen Lotion SPF 50 is a daily sun protection lotion...
Add to Cart
Healing Pharma India Pvt. Ltd Sunroof Sunscreen Lotion 60ml UVA/UVB SPF 50 for Daily Sun Protection
R 199.99 R 220.00
Add to Cart
Sebogel Salicylic Acid and Nicotinamide Gel 30g tube with box packaging and icons with white background UBIK Salicylic Acid and Nicotinamide Gel 30g for pimples tube front view
Quickshop Sebogel Salicylic Acid and Nicotinamide Gel is a daily acne care gel...
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UBIK Sebogel Salicylic Acid and Nicotinamide Gel 30g for Acne & Oily Skin
R 320.00 R 460.00
Add to Cart
REJSOL Vitamin C Hyaluronic Sheet Mask single use pouch front view with background
Quickshop A Medical-Grade Vitamin C and Hyaluronic face sheet mask that supports brighter,...
Add to Cart
REJSOL Vit C Hyaluronic Sheet Mask for Glow, Brightening & Hydration | REJSOL
R 89.99 R 119.99
Add to Cart
Imxia Minoxidil and Finasteride Topical Solution 5% 60ml bottle with box Minoxidil and Finasteride 5% topical solution with spray and dropper with white background
Quickshop A dual action topical solution with Minoxidil and Finasteride that supports hair...
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Imxia KLM Minoxidil and Finasteride Topical Solution 5% 60ml | KLM Imxia
R 499.99 R 599.99
Add to Cart
Buy Minoxidil topical solution USP 5% cost details with composition panel shown with whtie background Order derma roller for hair 0.5mm online, boxed product set shown in South Africa
Quickshop A precision derma roller for hair growth designed for scalp use only,...
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Derma Roller System Derma Roller for Hair Growth 0.5mm 540 Titanium Microneedle
R 120.00 R 149.00
Add to Cart
Minoxytop Minoxidil topical solution USP 5% 60ml box on white background Buy Minoxidil topical solution USP 5% 60ml bottle & box on white background
Quickshop Medical-Grade and USP-standard topical solution designed for scalp use 5% w/v strength...
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Healing Pharma India Pvt Ltd Minoxidil Topical Solution USP w/v 60ml | Minoxytop 5% for hair growth
R 249.99 R 265.00
Add to Cart
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Featured Creams

Tretiheal 0.025% tretinoin cream 20g tube and box and icons on white background Tretiheal tretinoin cream USP 0.025% 20g tube by Healing Pharma on white background
Quickshop Say goodbye to acne, breakouts, dull texture, and early lines. Tretiheal Tretinoin...
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Healing Pharma India Pvt Ltd Tretinoin Cream 0.025%, 20g Tretiheal for acne and wrinkles
R 379.99 R 449.99
Add to Cart
Tretiheal Tretinoin Cream USP 0.1% w/w 20g box and tube by Healing Pharma on white background Tretiheal 0.1% Tretinoin Cream USP 20g tube by Healing Pharma - front view
Quickshop Tretinoin Cream USP Tretiheal 0.1%, 20g by Healing Pharma is a high-strength...
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Healing Pharma India Pvt Ltd Tretiheal Tretinoin Cream 0.1%, 20g | Treatment Acne & Anti aging
R 389.99 R 499.99
Add to Cart
Tretiheal tretinoin cream USP 0.05% 20g box and tube on white background Tretiheal tretinoin cream 0.05% 20g tube on white background - front view
Quickshop Tretiheal Tretinoin Cream 0.05%, 20g treats acne, rough texture, and early lines.This...
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Healing Pharma India Pvt Ltd Tretiheal Tretinoin Cream 0.05% - Anti-Acne & Wrinkle | Healing Pharma
R 385.99 R 479.99
Add to Cart
Tretin Tretinoin Cream USP 0.05% w/w 30g tube with outer box and icons – front view Tretin Tretinoin Cream USP 0.05% 30g tube – front view
Quickshop Welcome to tretinoins.co.za your trusted online store to buy tretinoin cream south...
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Hegde & Hegde Pharmaceutical LLP Tretin 0.05% Tretinoin Cream 30g (H&H) | Anti-Acne & Anti-Wrinkle
R 519.99 R 599.99
Add to Cart
Tretinoin Cream 0.025%, Tretin 30g for Anti-Aging & Wrinkles Tretin 0.025% Tretinoin Cream USP w/w 30g tube – front view
Quickshop Say goodbye to breakouts and dull texture with tretinoin. Quick Facts of...
Add to Cart
Hegde & Hegde Pharmaceutical LLP Tretinoin Cream 0.025%, Tretin 30g for Anti-Aging & Wrinkles
R 499.99 R 579.99
Add to Cart
Sunroof Sunscreen Lotion SPF 50 60ml tube with original packaging and icons with white background Sunroof Sunscreen Lotion SPF 50 by healing pharma tube front view
Quickshop Medical-Grade Sunroof Sunscreen Lotion SPF 50 is a daily sun protection lotion...
Add to Cart
Healing Pharma India Pvt. Ltd Sunroof Sunscreen Lotion 60ml UVA/UVB SPF 50 for Daily Sun Protection
R 199.99 R 220.00
Add to Cart
Skinshine cream containing hydroquinone 2 percent tretinoin 0.025 percent and mometasone furoate 0.1 percent 15g pack Skinshine cream tube showing hydroquinone 2 percent tretinoin 0.025% & mometasone furoate 0.1% 15g
Quickshop Hydroquinone 2% w/w + Tretinoin 0.025% w/w + Mometasone Furoate 0.1% w/w...
Add to Cart
Cadila Pharmaceuticals Ltd Hydroquinone, Tretinoin and Mometasone Furoate Cream for Dark Patches
R 389.99 R 424.99
Add to Cart
Sebogel Salicylic Acid and Nicotinamide Gel 30g tube with box packaging and icons with white background UBIK Salicylic Acid and Nicotinamide Gel 30g for pimples tube front view
Quickshop Sebogel Salicylic Acid and Nicotinamide Gel is a daily acne care gel...
Add to Cart
UBIK Sebogel Salicylic Acid and Nicotinamide Gel 30g for Acne & Oily Skin
R 320.00 R 460.00
Add to Cart
REJSOL Vitamin C Hyaluronic Sheet Mask single use pouch front view with background
Quickshop A Medical-Grade Vitamin C and Hyaluronic face sheet mask that supports brighter,...
Add to Cart
REJSOL Vit C Hyaluronic Sheet Mask for Glow, Brightening & Hydration | REJSOL
R 89.99 R 119.99
Add to Cart
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Concerns

Choose the concern you want to treat — we’ll match you with the right bundle.

Save 5%

Melasma & Dark Patches Bundle

  • Azelaic Acid 20%, Tretinoin 0.025% & SPF 50 bundle
  • For melasma, dark patches (chubaba), acne marks & uneven tone
  • Save 5% vs buying separately — R921.47
More About Melasma
Save 5%

Hyperpigmentation & Dark Spots Bundle

  • Hydroquinone 4%, Tretinoin 0.025% & SPF 50 bundle
  • For dark spots, sun spots, post-acne marks (PIH) & uneven skin tone
  • Save 5% vs buying separately — R930.79
More About Hyperpigmentation

What is Tretinoin?

Tretinoin is a dermatologist-trusted vitamin A treatment used across South Africa for acne, wrinkles, and uneven skin tone. It speeds up cell renewal, keeps pores clear, and smooths skin texture.

Proven Skin Benefits

  • Acne Control → Clears clogged pores and reduces breakouts.
  • Wrinkle Reduction → Softens fine lines and improves elasticity.
  • Texture Renewal → Smooths tone and surface irregularities.
  • Even Complexion → Fades dark spots and restores balanced, healthy-looking skin.

Tretinoin Creams and Gels deliver visible results when used correctly under dermatological guidance. Regular use helps South Africans achieve clearer, smoother, more youthful-looking skin.

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what is Tretinoin
Tretinoin Cream South Africa

Lock In Your Tretinoin Routine & Save 5%

Our Tretinoin Bundles give you an automatic 5% discount, so you can stock up for months of treatment without running out.

  • Save 5% instantly – no coupon needed
  • Bundles cover 3–6 months of use
  • Options for acne, anti-ageing and pigmentation
Shop Tretinoin Bundles

Your Trusted Source for Tretinoin Cream in South Africa

We combine dermatology expertise with reliable service to deliver authentic tretinoin products trusted across South Africa.

Authenticity Guarantee

All creams and gels come directly from licensed South African and international pharmacy distributors. Every tube is genuine, sealed, and verified for quality.

Secure Packaging

Orders are packed in plain, secure parcels for your privacy. Fast local delivery — from checkout to your doorstep.

Pharmacy-Grade Quality

Each formula meets medical-grade standards and is reviewed by dermatologists for safety, purity, and visible results.

Delivered Last Week with SkyPoint & Pep Stores

A snapshot of recent customer parcels delivered through our SkyPoint couriers and Pep Store collection points.
We protect customer privacy by blurring personal details while still showing the parcel, order number, delivery date and route.

Order 1010
ORDER #1010
30-Nov-2024
FLAGS → MATSU
Dimakatso P.
Order 1009
ORDER #1009
30-Nov-2025
FLAGS → GLENA
Jane M.
Order 1008
ORDER #1008
30-Nov-2025
FLAGS → FOURW
Nadia M.
Order 1007
ORDER #1007
30-Nov-2025
FLAGS → BELLA
Saafiyah B.
Order 1006
ORDER #1006
30-Nov-2025
FLAGS → AKASI
Raymond S.
Order 1005
ORDER #1005
30-Nov-2025
FLAGS → DUNKE
Nick A.
Order 1004
ORDER #1004
30-Nov-2025
FLAGS → RUSTE
Nnamdi O.
Order 1003
ORDER #1003
30-Nov-2025
FLAGS → SANOT
Jacolene V.
Order 1015
ORDER #1015
3-Dec-2025
FLAGS → JHB
Tammy W.
Order 1012
ORDER #1012
05-Dec-2025
FLAGS → BENONl Gauteng
lily S.
Order 1013
ORDER #1013
30-Nov-2025
FLAGS → Langebaan Western Cape
Amanda C.
Order 1014
ORDER #1014
03-Dec-2025
FLAGS → Lephalale Limpopo
Carina G.
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Skincare Plans Made Just for You by Tretinoins
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Skincare Plans Made Just for You

Our tretinoin creams are adjusted for South African skin and weather. Each formula uses proven, dermatologist-approved ingredients to help you get clear, smooth, and healthy skin, safely and effectively.
GET FREE CONSULTATION

Payment & Delivery Options

Choose the option that fits your budget and timing in South Africa.

The Courier Guy – Recommended (R105)

The Courier Guy – Recommended (R105)

Recommended option. The Courier Guy collects from us almost daily (Monday to Friday, working days only). After pickup, delivery takes about 4–5 working days to your door.

Pep Store Collection – Saver (R75)

Pep Store Collection – Saver (R75)

Pay R75 and collect your parcel from your nearest Pep Store. Share your closest Pep Store name or store code at checkout so we can ship it there. Delivery time: about 8–10 working days to reach the Pep Store.

Pep Store Collection – Express (R120)

Pep Store Collection – Express (R120)

Pay R120 for a faster Pep Store collection. You still give your nearest Pep Store name or code, we ship it there for you. Delivery time: about 3–5 working days to reach the Pep Store.

Door-to-Door Delivery – SkyPoint (R165)

Door-to-Door Delivery – SkyPoint (R165)

Pay R165 for direct delivery to your door via SkyPoint couriers. The driver collects parcels from us 3 days a week, then delivers in around 5 working days after pickup.

Frequently Asked Questions

Is Tretinoin Cream Safe to Use?

Yes, tretinoin is safe when used as directed by a skincare professional. Always follow your dermatologist’s guidance for best results.

Yes, tretinoin is a prescription-only treatment in South Africa. Our team helps connect you with licensed professionals for safe access.

Most South African orders arrive within 3–5 business days. Every parcel is trackable and packed discreetly.

Yes. All tretinoin creams are authentic and pharmacy-sourced from verified suppliers. We never sell imitations or unsafe alternatives.

Orders are shipped directly from licensed South African and regional pharmacy partners, ensuring quality and local compliance.

Yes, but introduce tretinoin slowly. Avoid harsh exfoliants or strong acids at the same time. Always apply moisturiser after use.

Visible changes often appear within 4–8 weeks, with clearer, smoother skin improving over time. Consistency is key.

Tretinoin Guides & Updates

Trusted tretinoin guides for South Africa

What Is a Vitamin C Hyaluronic Sheet Mask & How It Works

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What Is a Vitamin C Hyaluronic Sheet Mask & How It Works

Hydroquinone + Tretinoin + Mometasone | Uses, Benefits, & Side Effects

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What is hydroquinone tretinoin and mometasone furoate Skinshine cream used for?
Tretinoin 0.025 vs 0.05 | Which Strength Is Right for Your Skin

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Tretinoin 0.025 vs 0.05 | Which Strength Should You Start With
Hydroquinone Cream South Africa for Melasma and Dark Spots

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Hydroquinone Cream for Dark Spots and Melasma in South Africa

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Tretinoins Cream Store

We deliver prescription strength tretinoin across South Africa. Every product is genuine, pharmacy verified, and packed with care for privacy.

Customer Service

Customer Service

Contact Us

Contact Us

Email: contact@tretinoins.co.za
WhatsApp: +27 68 067 4421
Hours: Mon-Fri 9AM-6PM EST
Address: FlagStaff 4810, Eastern Cape, South Africa
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